Fact Sheet

Automating PV Literature Surveillance for Adverse Events

For pharmacovigilance (PV) teams, scientific and medical literature is the fourth largest source of adverse event (AE) reports received by the FDA. The growing volume of scientific literature is further compounded by the lack of a standard way for managing literature surveillance.

Used by 50% percent of the world’s top pharmaceutical companies, DistillerSR provides your team with a fully validated literature surveillance platform to process ICSRs and safety signals in an automated, real-time, and audit-ready manner.

Shield with Checkmark Icon

A Single Source of Trusted Evidence

Easily demonstrate that journals are regularly searched and that screening and extraction are conducted and completed in a timely manner with DistillerSR’s completely transparent process. Drug safety teams gain real-time insight into all project and account activity to access a complete audit trail and to ensure regulatory compliance.

^

Fully Transparent, Secure, & Audit Ready

DistillerSR allows drug safety managers to create fully defensible, transparent, audit-ready, and reproducible reviews. The literature review software tracks all review activity and makes it easy to view the provenance of every cell of data. You can restrict access and ensure your data meets your organization’s security standards through Single Sign-On and user permissions.

^

Follow-the-Sun Collaboration & Oversight

Drug safety teams can collaborate more effectively, with standard processes in place and reduced management overhead. Reviewers are automatically assigned and notified of new work — regardless of the number of projects they are working on. Furthermore, all of their incomplete work is accessible from one central location. Team members can view real-time user and project metrics to gain insight into individual workloads, participation, quality, and performance.

^

Direct Integrations For Seamless Workflow

Synchronize your triage data seamlessly across all applications with DistillerSR’s API. Keep your safety databases and reporting dashboards up-to-date automatically in real-time, making submissions to regulating authorities seamless.

Import DistillerSR Reports to Third-party Safety Databases

DistillerSR’s public API allows the platform to be securely integrated with a broader technology ecosystem, including safety databases, signal detection and predictive analytics applications, reporting systems, data lakes, and others.

Clock Icon

Do More Faster and Smarter

DistillerSR automates many review tasks while providing real-time access to new and updated literature. DistillerSR allows you to find what you need quickly while easily sorting through irrelevant materials.

^

Real-Time Literature Surveillance

Newly published citations are automatically added to your surveillance review as soon as they become available by leveraging auto-alerts from data providers, such as Ovid, ProQuest, and Embase. Your team is automatically notified and can instantly assess the new literature for review, meanwhile, duplicates, can easily be identified and removed.

^

Easy-to-Use, Cost-Effective Full-Text Retrieval

Copyright compliant full-text documents can be automatically retrieved and added to your literature surveillance process. Safety teams can leverage their Article Galaxy and RightFind subscriptions to order documents from within DistillerSR for the lowest possible cost.

^

Instant Access to Source Materials

DistillerSR is connected directly to source materials stored in your organizations’ e-Library and through DOI.org. This eliminates the tedious task of searching for and uploading full-text documents.

AI Icon

Artificial Intelligence (AI) Reduces Screening Times & Improves Review Quality

DistillerSR automates many review tasks while providing real-time access to new and updated literature. DistillerSR allows you to find what you need quickly while easily sorting through irrelevant materials. DistillerSR’s AI increases literature triage efficiency to help you identify new AEs, stay on top of processing deadlines, and remain regulatory compliant.

^

Find Relevant References Faster

With the help of AI, DistillerSR allows you to find what you need quickly and easily by sorting through irrelevant materials. Its AI differentiates between relevant and irrelevant records, continuously reprioritizing the remaining, as-yet-unscreened records, and then presents them to reviewers based on the likelihood of relevance.

On average, you can find most of your relevant references between 40–60% sooner than conventional screening. This allows you to start working on other stages of the review faster.

^

Prevent Erroneous Exclusions

DistillerSR’s AI can also help you confirm that you haven’t accidentally excluded any references – it does this by double-checking your exclusions for errors, increasing your confidence in your screening decisions. Conflicts and disagreements between reviewers, meanwhile, are automatically identified and set aside for easy resolution.

Gear Icon

Take Control of Your Reviews – The Way You Want

DistillerSR easily lets you configure and standardize your workflows to the specific regulatory requirements of different health jurisdictions and internal literature surveillance and triage processes.

^

Create & Reuse Templates To Meet Regional Standards

The literature review software allows you to extract, appraise, and report on data in a way that fits your regional and organizational requirements. Furthermore, you can instantly reuse and then modify the captured data, workflow, and reports across multiple reviews by creating templates for other projects.

^

Eliminate Time Wasted Data Cleaning

DistillerSR helps to reduce human error by requiring data validation at the time of extraction, such as using pre-specified acceptable ranges for numerical values. Configured to meet your requirements, DistillerSR’s in-form data validation lets your team spend less time and effort to acquire analysis-ready data.

For pharmacovigilance teams, monitoring existing and new literature for adverse events across often diverse drug portfolios is a highly manual and time-consuming effort. DistillerSR automates and streamlines PV literature surveillance for transparent, audit-ready, and compliant reporting.

DistillerSR ensures PV literature surveillance is efficient, compliant, and audit ready.

For pharmacovigilance teams, monitoring existing and new literature for adverse events across often diverse drug portfolios is a highly manual and time-consuming effort. DistillerSR automates and streamlines PV literature surveillance for transparent, audit-ready, and compliant reporting.

Download the PDF version of this fact sheet



Learn More About DistillerSR

Phamacovigilance Vertical Triangle
Phamacovigilance Vertical Triangle